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Glucagonoma (glucagon + - oma) is a malignant tumor originating from the alpha cells of the islet apparatus of the pancreas. Sildenafil is located in various parts of the pancreas, abundantly vascularized and closely connected with the vessels. The size of the tumor is 4-10 cm in diameter, the shape is different - from spherical to order viagra online, the weight can reach 50 g.
Tumor cells are usually pleomorphic, with a large nucleus and one large nucleolus. Histochemically, they give positive reactions for argyrophilicity, chromium-hematoxylin-phloxin, paraaminobenzaldehyde, the reaction with aldehyde-fuchsin is negative. Electron microscopy reveals a significantly larger alpha cell size in the tumor compared to the normal gland. It is clinically manifested by diabetes mellitus (see Diabetes mellitus), which occurs in the early stages of the tumor process and is characterized by the absence of ketoacidosis and hypoglycemia. The disappearance of the papillae of the tongue is characteristic (the so-called varnished tongue).
Diagnosis is based on a wedge, data and laboratory researches (determination of content of sugar in blood and urine, glucagon in blood). In view of the rapid occurrence of metastases, scanning of the pancreas, arteriography of the truncus celiacus system, puncture biopsy of the tumor, and sometimes diagnostic laparotomy are important. Treatment is operative. In order to compensate for diabetes, insulin therapy is prescribed).
The prognosis after surgery is uncertain. A relapsing course of the disease is characteristic, irritability, insomnia, and headaches are often noted. The diagnosis is made on the basis of the determination of helminths extracted from the mucous membrane. The prognosis is favorable when removing helminths. The meaning of the word gongylonematosis. Gongylonematosis in the crossword dictionary. Gongylonematosis (gongylonemosis) is a helminthiasis from the group of nematodosis caused by Gongylonema pulchrum and characterized by the formation of small papules and erosions on the mucous membrane of the oral cavity and esophagus, stomatitis and pharyngitis.